Rutin is used as a vascular protectant, reducing capillary permeability and fragility, varicose veins, internal bleeding, hemorrhoids, inflammatory bowel disease (IBD), to prevent strokes, and for prophylaxis of mucositis associated with cancer treatments. Rutin is a powerful antioxidant, decreases inflammation, prevents tumor growth, and decreases platelet aggregation. In combination with trypsin and bromelain, rutin is used orally for osteoarthritis.